• The importance of estrogen is

  2019-04-29

  

  The importance of estrogen is maintaining bone health is well recognized [25,26]. The bone microenvironment is dynamic with on-going remodeling through the activity of both osteoclasts (bone resorption) and osteoblasts (bone formation). Osteoclastogenesis is tightly regulated by the receptor activat

• Facing a unique clinical case of osteosarcoma recurrence fol

  2019-04-29

  

  Facing a unique clinical case of osteosarcoma recurrence following autologous adipose-tissue transfer [30], we started to investigate the interactions between osteosarcoma and adipose tissue by using pre-clinical experiments [30,64]. In the present report, we compared the interactions of MNNG-HOS ce

• Presence of trisomy raises the possibility of added gene dos

  2019-04-29

  

  Presence of trisomy raises the possibility of added gene dose contributing to the leukemogenic process. The oncogene, c-kit, is localized to chromosome 4. Leukemic blasts of our patient strongly expressed c-kit. c-Kit expression was not studied in the other 4 reported cases of MPAL. Increased expres

• br In Jun Zhu and

  2019-04-28

  

  In , Jun Zhu and colleagues provide stillbirth rates retrieved from China\'s National Maternal Near Miss Surveillance System between 2012 and 2014. The authors found the stillbirth rate was particularly high in young women (aged was significantly higher than WHO\'s recommended proportion. The one-

• buy olda Therefore other imaging techniques and

  2019-04-28

  

  Therefore, other imaging techniques and tools have been evaluated. The results of this study add to the body of evidence demonstrating the value of SPECT and the need for a multifactorial approach to patient selection for CRT and in evaluating potential predictors of CRT response in non-ischemic pat

• br Conclusion br Conflict of Interest statement br Acknowled

  2019-04-28

  

  Conclusion Conflict of Interest statement Acknowledgments We thank the generous support of Bratty Family Fund, Michael and Karyn Goldstein Cancer Research Fund, Pulenzas Cancer Research Fund, Joseph and Silvana Melara Cancer Research Fund, and Ofelia Cancer Research Fund. Introduction P

• Introduction Dabigatran Boehringer Ingelheim Ingelheim Germa

  2019-04-28

  

  Introduction Dabigatran (Boehringer Ingelheim, Ingelheim, Germany) is a direct thrombin inhibitor, which can be orally administered, and is used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). In early phase studies of dabigatran in healthy men, pla

• cytotoxicity assay br Material and methods br Results br Dis

  2019-04-28

  

  Material and methods Results Discussion Conclusions Disclosures Conflict of interest Financial support Introduction Stroke is one of the top five common causes of mortality in Malaysia with a rate at 8.43/100,000 cytotoxicity assay [1,2]. Stroke impact is not limited to phys

• br The achievement of an AIDS free future

  2019-04-28

  

  The achievement of an AIDS-free future will surely be a priority discussion topic at the upcoming International AIDS Society conference in Melbourne, Australia. The discovery that antiretroviral therapy (ART) limits HIV transmission follows several years of steady progress in controlling the epide

• order SL-327 Este n mero correspondiente al primer semestre

  2019-04-28

  

  Este número, correspondiente al primer semestre del año 2013, se abre con una sección dedicada order SL-327 reflexionar sobre América Latina desde diferentes puntos cardinales: literatura, ciencia y tecnología, derechos humanos, filosofía, historia de las ideas y dos perspectivas del pensamiento de

• br Introducci n br Y si digo populismo

  2019-04-28

  

  Introducción ¿ Y si digo populismo? Populismo es, quizá, el concepto que con más particularidad y persistencia se ha utilizado para describir y analizar (y evaluar) la política en América Latina. La emergencia de fenómenos políticos que desafiaron las categorías tanto de la sociología política

• The IMCI algorithms have been developed and

  2019-04-28

  

  The IMCI algorithms have been developed and endorsed by WHO in the 1990s and most low-income and middle-income countries are using them. The IMCI strategy algorithms are not only for diarrhoea but also other common childhood illnesses, such as pneumonia. These countries have invested heavily in trai

• For the relationship between the PVAB and FFRWs

  2019-04-28

  

  For the relationship between the PVAB and FFRWs, setting the PVAB period as short as possible is considered optimal, because not all patients necessarily have problems with FFRWs [4,6]. However, the Medtronic pacemakers investigated in this study had minimum PVAB values as short as 110ms or 130ms, w

• The pre procedural venogram showed total occlusion of

  2019-04-28

  

  The pre-procedural venogram showed total occlusion of the left BCV and the formation of an acute angle between the right BCV and SVC caused by tuberculosis-induced lung destruction (Fig. 1A and B). We adopted a right-sided venous approach via the right subclavian vein (SCV) for a single chamber. In

• br Discussion and outstanding questions Reproductive endocri

  2019-04-28

  

  Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multifa

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