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br Medicinal properties M oleifera is often
2018-11-06
Medicinal properties M. oleifera is often referred as a panacea and can be used to cure more than 300 diseases. Moringa has long been used in herbal medicine by Indians and Africans. The presence of phytochemicals makes it a good medicinal agent. In this section, the effect of moringa on diseases
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br Materials and methods br Results and discussion br Conclu
2018-11-06
Materials and methods Results and discussion Conclusion Silver nanoparticles are produced by the reduction of silver ions to colloidal silver. The present studies were confirmed the formation of silver nanoparticles using N. nimmoniana fruit extract from UV–vis, XRD, FE-SEM, and with EDX an
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We conclude that we have established xeno
2018-11-06
We conclude, that we have established xeno-free fibroblast feeder cell lines using HS-containing culture medium and, in accordance with published data agree, that HS is a feasible substitute for FBS (Richards et al., 2003; Kibschull et al., 2011; Ellerstrom et al., 2006; Meng et al., 2008; Unger et
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Unspecific amplification of gene expression exploits informa
2018-11-06
Unspecific amplification of gene expression exploits information intrinsic to cells, initiating a self-organizing circuitry, where gene expression cascades propagate and interact, much like the propagation of microscopic fluctuations within a critical iron magnet. Unlike an iron magnet, the circuitr
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stavudine br Conclusion br Materials and methods br Acknowle
2018-11-06
Conclusion Materials and methods Acknowledgments We thank M. Dubrovcakova and V. Frivalska for excellent technical assistance. We are grateful to J. Zmajkovic for technical help with fluorescence microscopy, J. Lakota, M.D. for providing us with material and M. Cihova for critical reading o
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br Introduction Stem cell divisions resulting
2018-11-06
Introduction Stem cell divisions resulting in alternative pathways of self-renewal or differentiation require very distinctive epigenetic regulation of gene expression from the same genome. Where division has a symmetrical output of progeny cells, the assumption is that the molecular signatures d
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br Introduction Epidermal stem cells SCs are localized in
2018-11-06
Introduction Epidermal stem motilin receptor (SCs) are localized in several well-defined cellular compartments with the best-studied being an anatomical area of the hair follicle (HF) known as “bulge” (Blanpain and Fuchs, 2009; Cotsarelis et al., 1990; Jaks et al., 2010). This unique anatomical
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br Introduction Transplantation of hepatocytes
2018-11-06
Introduction Transplantation of hepatocytes (HTx) has been shown to be useful for patients with chronic or acute liver failure or genetic defects in liver function (Strom et al., 1997; Fisher et al., 2000; Fisher and Strom, 2006; Strom et al., 2006; Fox et al., 1998; Horslen et al., 2003; Muraca
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To further investigate the HSP signaling pathway
2018-11-06
To further investigate the HSP90 signaling pathway we inhibited the downstream molecule PI3K, which is involved in cell migration and MAPK Inhibitor Library signaling (Fukata et al., 2003; Yoneda et al., 2005; Zhu et al., 2009b). Migration signaling involves the Rac GTPase interacting protein, whic
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Stem cell factors and cancer
2018-11-06
Stem cell factors and cancer development OCT4 OCT4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain class 5 transcription factor 1) belongs to the family of POU-domain transcription factors and is considered to be the key factor in maintaining and inducing pluripotency
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br Materials and methods br Results and discussion
2018-11-06
Materials and methods Results and discussion To generate an OKSM mouse model with higher reprogramming efficiency we exchanged the m2rtTA for the more efficient rtTA3 (Das et al., 2004). We used founder animals which can be found commercially available at the Jackson Institute and applied a br
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Thus it appears that in the adult SVZ
2018-11-06
Thus, it appears that in the adult SVZ, in the absence or low levels of Noggin, BMP proteins expressed by astrocytes and NSC bind and activate BMPR, presumably BMPR-1A, activating its downstream SMAD proteins. Activated SMADs up-regulate the expression of the miRNA coding gene Mirg which encodes mi
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Subsequently these expanded effector cells were
2018-11-06
Subsequently, these expanded effector D609 were examined for their cytotoxicity activity (PI% and LDH release) against targets, where they also showed strong killing of the K562 leukemia cell line. However, the observation of the slight cytotoxicity induced by fresh effector cells suggests proper a
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During the last decade significant progress has been made in
2018-11-05
During the last decade, significant progress has been made in achieving hematopoietic differentiation from hPSCs. Multiple protocols for hematopoietic differentiation have been developed and have made it possible to routinely produce blood stavudine for experimentation. However, generating HSCs wit
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EFNB encodes EPHRIN B a member of the Eph
2018-11-05
EFNB1 encodes EPHRIN-B1, a member of the Eph/ephrin family of membrane-linked signaling molecules, and abnormal signaling between bcr-abl inhibitor expressing wild-type EPHRIN-B1 and cells that are functionally EPHRIN-B1-null may occur in the mosaic state (Compagni et al., 2003; Wieacker and Wieland
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